References

Expression profiling of microRNA using real-time quantitative PCR, how to use it and what is available.
Benes, V. & Castoldi, M.
Methods. 2010 Jan 25.
PubMed

An assessment of air as a source of DNA contamination encountered when performing PCR.
Witt, N., Rodger, G., Vandesompele, J., Benes, V., Zumla, A., Rook, G.A. & Huggett, J.F.
J Biomol Tech. 2009 Dec;20(5):236-40.
PubMed

Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth.
Maillot, G., Lacroix-Triki, M., Pierredon, S., Gratadou, L., Schmidt, S., Benes, V., Roche, H., Dalenc, F., Auboeuf, D., Millevoi, S. & Vagner, S.
Cancer Res. 2009 Nov 1;69(21):8332-40. Epub 2009 Oct 13.
PubMed

Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma.
Hose, D., Reme, T., Meissner, T., Moreaux, J., Seckinger, A., Lewis, J.D., Benes, V., Benner, A., Hundemer, M., Hielscher, T., Shaughnessy JD, J.r, Barlogie, B., Neben, K., Kramer, A., Hillengass, J., Bertsch, U., Jauch, A., De Vos, J., Rossi, J.F., Mohler, T., Blake, J., Zimmermann, J., Klein, B. & Goldschmidt, H.
Blood. 2009 Apr 30;113(18):4331-40. Epub 2009 Jan 26.
PubMed

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments.
Bustin, S.A., Benes, V., Garson, J.A., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M.W., Shipley, G.L., Vandesompele, J. & Wittwer, C.T.
Clin Chem. 2009 Apr;55(4):611-22. Epub 2009 Feb 26.
PubMed

Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.
Weinmann, L., Hock, J., Ivacevic, T., Ohrt, T., Mutze, J., Schwille, P., Kremmer, E., Benes, V., Urlaub, H. & Meister, G.
Cell. 2009 Feb 6;136(3):496-507. Epub 2009 Jan 22.
PubMed

Aging and replicative senescence have related effects on human stem and progenitor cells.
Wagner, W., Bork, S., Horn, P., Krunic, D., Walenda, T., Diehlmann, A., Benes, V., Blake, J., Huber, F.X., Eckstein, V., Boukamp, P. & Ho, A.D.
PLoS One. 2009 Jun 9;4(6):e5846.
PubMed

MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer.
Lowery, A.J., Miller, N., Devaney, A., McNeill, R.E., Davoren, P.A., Lemetre, C., Benes, V., Schmidt, S., Blake, J., Ball, G. & Kerin, M.J.
Breast Cancer Res. 2009;11(3):R27. Epub 2009 May 11.
PubMed

RNA degradation compromises the reliability of microRNA expression profiling.
Ibberson, D., Benes, V., Muckenthaler, M.U. & Castoldi, M.
BMC Biotechnol. 2009 Dec 21;9:102.
PubMed

Transcriptome complexity in a genome-reduced bacterium.
Guell M., van Noort V., Yus E., Chen W.-H., Leigh-Bell J., Michalodimitrakis K., Yamada T., Arumugam M., Doerks T., Kuehner S., Rode M., Suyama M., Gavin, A.C., Bork, P. and Serrano L.
Science 2009 326 1268-1271

Cyclical DNA methylation of a transcriptionally active promoter.
Metivier, R., Gallais, R., Tiffoche, C., Le Peron, C., Jurkowska, R.Z., Carmouche, R.P., Ibberson, D., Barath, P., Demay, F., Reid, G., Benes, V., Jeltsch, A., Gannon, F. & Salbert, G.
Nature. 2008 Mar 6;452(7183):45-50.
PubMed

Transient cyclical methylation of promoter DNA.
Kangaspeska, S., Stride, B., Metivier, R., Polycarpou-Schwarz, M., Ibberson, D., Carmouche, R.P., Benes, V., Gannon, F. & Reid, G.
Nature. 2008 Mar 6;452(7183):112-5.
PubMed

Hfe acts in hepatocytes to prevent hemochromatosis.
Vujic Spasic, M., Kiss, J., Herrmann, T., Galy, B., Martinache, S., Stolte, J., Grone, H.J., Stremmel, W., Hentze, M.W. & Muckenthaler, M.U.
Cell Metab. 2008 Feb;7(2):173-8.
PubMed

Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis.
Hung, L.H., Heiner, M., Hui, J., Schreiner, S., Benes, V. & Bindereif, A.
RNA. 2008 Feb;14(2):284-96. Epub 2007 Dec 11.
PubMed

Transcriptome profiling of estrogen-regulated genes in human primary osteoblasts reveals an osteoblast-specific regulation of the insulin-like growth factor binding protein 4 gene.
Denger, S., Bahr-Ivacevic, T., Brand, H., Reid, G., Blake, J., Seifert, M., Lin, C.Y., May, K., Benes, V., Liu, E.T. & Gannon, F.
Mol Endocrinol. 2008 Feb;22(2):361-79. Epub 2007 Oct 25.
PubMed

Replicative senescence of mesenchymal stem cells: a continuous and organized process.
Wagner, W., Horn, P., Castoldi, M., Diehlmann, A., Bork, S., Saffrich, R., Benes, V., Blake, J., Pfister, S., Eckstein, V. & Ho, A.D.
PLoS ONE. 2008 May 21;3(5):e2213.
PubMed

miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes.
Castoldi, M., Schmidt, S., Benes, V., Hentze, M.W. & Muckenthaler, M.U.
Nat Protoc. 2008;3(2):321-9.
PubMed

Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression.
Marro, S., Barisani, D., Chiabrando, D., Fagoonee, S., Muckenthaler, M.U., Stolte, J., Meneveri, R., Haile, D., Silengo, L., Altruda, F. & Tolosano, E.
Gastroenterology. 2007 Oct;133(4):1261-1271.
PubMed

miChip: a microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes.
Castoldi, M., Benes, V., Hentze, M.W. & Muckenthaler, M.U.
Methods. 2007 Oct;43(2):146-52.
PubMed

Life cycle transcriptome of the malaria mosquito Anopheles gambiae and comparison with the fruitfly Drosophila melanogaster.
Koutsos, A.C., Blass, C., Meister, S., Schmidt, S., MacCallum, R.M., Soares, M.B., Collins, F.H., Benes, V., Zdobnov, E., Kafatos, F.C. & Christophides, G.K.
Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11304-9. Epub 2007 Jun 11.
PubMed

Pax-Six-Eya-Dach network during amphioxus development: conservation in vitro but context specificity in vivo.
Kozmik, Z., Holland, N.D., Kreslova, J., Oliveri, D., Schubert, M., Jonasova, K., Holland, L.Z., Pestarino, M., Benes, V. & Candiani, S.
Dev Biol. 2007 Jun 1;306(1):143-59. Epub 2007 Mar 13.
PubMed

Physiologic systemic iron metabolism in mice deficient for duodenal Hfe.
Spasic, M.V., Kiss, J., Herrmann, T., Kessler, R., Stolte, J., Galy, B., Rathkolb, B., Wolf, E., Stremmel, W., Hentze, M.W. & Muckenthaler, M.U.
Blood. 2007 May 15;109(10):4511-7. Epub 2007 Jan 30.
PubMed

Modular Proteins from the Drosophila sallimus (sls) Gene and their Expression in Muscles with Different Extensibility.
Burkart, C., Qiu, F., Brendel, S., Benes, V., Haag, P., Labeit, S., Leonard, K. & Bullard, B.
J Mol Biol. 2007 Jan 27;.
PubMed

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation.
Verga Falzacappa, M.V., Vujic Spasic, M., Kessler, R., Stolte, J., Hentze, M.W. & Muckenthaler, M.U.
Blood. 2007 Jan 1;109(1):353-8. Epub 2006 Aug 31.
PubMed

Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy.
Sanchez, M., Galy, B., Dandekar, T., Bengert, P., Vainshtein, Y., Stolte, J., Muckenthaler, M.U. & Hentze, M.W.
J Biol Chem. 2006 Aug 11;281(32):22865-74. Epub 2006 Jun 7.
PubMed

A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA).
Castoldi, M., Schmidt, S., Benes, V., Noerholm, M., Kulozik, A.E., Hentze, M.W. & Muckenthaler, M.U.
RNA. 2006 May;12(5):913-20. Epub 2006 Mar 15.
PubMed

The molecular elasticity of the insect flight muscle proteins projectin and kettin.
Bullard, B., Garcia, T., Benes, V., Leake, M.C., Linke, W.A. & Oberhauser, A.F.
Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4451-6. Epub 2006 Mar 14.
PubMed

Adhesion of hematopoietic progenitor cells to hurnan mesenchymal stromal cells as a model for interaction between stem cells and their niche.
Wagner, Wolfgang; Wein, Frederik; Roderburg, Christoph; Benes, Vladimir; Diehlmann, Anke; Krause, Ulf; Frankhauser, Maria; Wuchter, Patrick; Volker, Eckstein; Ho, Anthony D.
Blood November 2006 108(11)

Proteomic analysis of nasal aspirates derived from children suffering influenza virus infection.
Teran, LM; Ruggeberg, S; Hernandez, JL; Fuentes-Arenas, F; Franz, T
Molecular & Cellular Proteomics October 2006 5(10)

Targeted disruption of the mouse mitoferrin (Slc25A37) mitochondrial solute carrier results in defective primitive and definitive erythropoiesis.
Paw, Barry H.; Gwynn, Babette; Langer, Nathaniel B.; Shaw, George C.; Lambert, Amy J.; Boyer, Leah A.; Li, Liangtao; Stolte, Jens; Robledo, Raymond F.; Sahr, Kenneth E.; Schlaeger, Thorsten M.; Hentze, Matthias W.; Muckenthaler, Martina U.; Kaplan, Jerry; Peters, Luanne L.
Blood November 2006 108(11)

Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii.
Raible, F., Tessmar-Raible, K., Osoegawa, K., Wincker, P., Jubin, C., Balavoine, G., Ferrier, D., Benes, V., de Jong, P., Weissenbach, J., Bork, P. & Arendt, D.
Science 2005 Nov 25;310(5752):1325-6.
PubMed

Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A.
Reid, G., Metivier, R., Lin, C.Y., Denger, S., Ibberson, D., Ivacevic, T., Brand, H., Benes, V., Liu, E.T. & Gannon, F.
Oncogene 2005 Jul 21;24(31):4894-907.
PubMed

Quantitative real-time RT-PCR – a perspective.
Bustin, S.A., Benes, V., Nolan, T. & Pfaffl, M.W.
J Mol Endocrinol 2005 Jun;34(3):597-601.
PubMed

Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodgkin lymphoma cells.
Relogio, A., Ben-Dov, C., Baum, M., Ruggiu, M., Gemund, C., Benes, V., Darnell, R.B. & Valcarcel, J.
J Biol Chem 2005 Feb 11;280(6):4779-84. Epub 2004 Nov 16.
PubMed

Transcriptional complexes engaged by apo-estrogen receptor-alpha isoforms have divergent outcomes.
Metivier, R., Penot, G., Carmouche, R.P., Hubner, M.R., Reid, G., Denger, S., Manu, D., Brand, H., Kos, M., Benes, V. & Gannon, F.
EMBO J 2004 Sep 15;23(18):3653-66. Epub 2004 Sep 02.
PubMed

Characterization of an Escherichia coli elaC deletion mutant.
Schilling, O., Ruggeberg, S., Vogel, A., Rittner, N., Weichert, S., Schmidt, S., Doig, S., Franz, T., Benes, V., Andrews, S.C., Baum, M. & Meyer-Klaucke, W.
Biochem Biophys Res Commun 2004 Aug 6;320(4):1365-73.
PubMed

Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo.
Galy, B., Ferring, D., Benesova, M., Benes, V. & Hentze, M.W.
RNA 2004 Jul;10(7):1019-25.
PubMed

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
Roy, C.N., Custodio, A.O., de Graaf, J., Schneider, S., Akpan, I., Montross, L.K., Sanchez, M., Gaudino, A., Hentze, M.W., Andrews, N.C. & Muckenthaler, M.U.
Nat Genet 2004 May;36(5):481-5. Epub 2004 Apr 18.
PubMed

ET recombination: DNA engineering using homologous recombination in E. coli.
Muyrers, J.P., Zhang, Y., Benes, V., Testa, G., Rientjes, J.M. & Stewart, A.F.
Methods Mol Biol 2004;256:107-21.
PubMed

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.
Muckenthaler, M., Roy, C.N., Custodio, A.O., Minana, B., deGraaf, J., Montross, L.K., Andrews, N.C. & Hentze, M.W.
Nat Genet 2003 May;34(1):102-7.
PubMed

Standardization of protocols in cDNA microarray analysis.
Benes, V. & Muckenthaler, M.
Trends Biochem Sci 2003 May;28(5):244-9.
PubMed

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.
Testa, G., Zhang, Y., Vintersten, K., Benes, V., Pijnappel, W.W., Chambers, I., Smith, A.J., Smith, A.G. & Stewart, A.F.
Nat Biotechnol 2003 Apr;21(4):443-7.
PubMed

Cloning and developmental expression of amphioxus Dachschund.
Candiani, S., Kreslova, J., Benes, V., Oliveri, D., Castagnola, P., Pestarino, M. & Kozmik, Z.
Gene Expr Patterns 2003 Mar;3(1):65-9.
PubMed

Automatisierte DNA-Extraktion durch Kombination von Liquid Handling und
Zentrifugation

Zimmermann, J., Zinn, T., Benes, V., Ibberson, D., Boulin, C., Griebel, R., Lomax, P., Mausel, M., Schubell, U. & Gunther-Eberle, K.
Laborwelt 2003 4(5) 41-42

Small is beautiful: Flexible Automatisierunginsel in der genomischen Forschung.
Zimmermann, J., Schmidt, S., Benes, V., Boulin, C., Griebel, R., Lomax, P., Zinn, T., Mausel, M., Schubell, U. & Gunther-Eberle, K.
Biospektrum 2003 9 764-766

The genome sequence of the malaria mosquito Anopheles gambiae.
Holt, R.A., Subramanian, G.M., Halpern, A., Sutton, G.G., Charlab, R., Nusskern, D.R., Wincker, P., Clark, A.G., Ribeiro, J.M., Wides, R., Salzberg, S.L., Loftus, B., Yandell, M., Majoros, W.H., Rusch, D.B., Lai, Z., Kraft, C.L., Abril, J.F., Anthouard, V., Arensburger, P., Atkinson, P.W., Baden, H., de Berardinis, V., Baldwin, D., Benes, V., Biedler, J., Blass, C., Bolanos, R., Boscus, D., Barnstead, M., Cai, S., Center, A., Chatuverdi, K., Christophides, G.K., Chrystal, M.A., Clamp, M., Cravchik, A., Curwen, V., Dana, A., Delcher, A., Dew, I., Evans, C.A., Flanigan, M., Grundschober-Freimoser, A., Friedli, L., Gu, Z., Guan, P., Guigo, R., Hillenmeyer, M.E., Hladun, S.L., Hogan, J.R., Hong, Y.S., Hoover, J., Jaillon, O., Ke, Z., Kodira, C., Kokoza, E., Koutsos, A., Letunic, I., Levitsky, A., Liang, Y., Lin, J.J., Lobo, N.F., Lopez, J.R., Malek, J.A., McIntosh, T.C., Meister, S., Miller, J., Mobarry, C., Mongin, E., Murphy, S.D., O'Brochta, D.A., Pfannkoch, C., Qi, R., Regier, M.A., Remington, K., Shao, H., Sharakhova, M.V., Sitter, C.D., Shetty, J., Smith, T.J., Strong, R., Sun, J., Thomasova, D., Ton, L.Q., Topalis, P., Tu, Z., Unger, M.F., Walenz, B., Wang, A., Wang, J., Wang, M., Wang, X., Woodford, K.J., Wortman, J.R., Wu, M., Yao, A., Zdobnov, E.M., Zhang, H., Zhao, Q., Zhao, S., Zhu, S.C., Zhimulev, I., Coluzzi, M., della Torre, A., Roth, C.W., Louis, C., Kalush, F., Mural, R.J., Myers, E.W., Adams, M.D., Smith, H.O., Broder, S., Gardner, M.J., Fraser, C.M., Birney, E., Bork, P., Brey, P.T., Venter, J.C., Weissenbach, J., Kafatos, F.C., Collins, F.H. & Hoffman, S.L.
Science 2002 Oct 4;298(5591):129-49.
PubMed

A genomic switch at the transition from cell proliferation to terminal differentiation in the Drosophila eye.
Jasper, H., Benes, V., Atzberger, A., Sauer, S., Ansorge, W. & Bohmann, D.
Dev Cell 2002 Oct;3(4):511-21.
PubMed

Functional equivalency of amphioxus and vertebrate Pax258 transcription factors suggests that the activation of mid-hindbrain specific genes in vertebrates occurs via the recruitment of Pax regulatory elements.
Krelova, J., Holland, L.Z., Schubert, M., Burgtorf, C., Benes, V. & Kozmik, Z.
Gene 2002 Jan 9;282(1-2):143-50.
PubMed

An estimate of large-scale sequencing accuracy.
Hill, F., Gemund, C., Benes, V., Ansorge, W. & Gibson, T.J.
EMBO Rep. 2000 Jul;1(1):29-31.
PubMed